Jiangsu Vanguard Pharmaceutical Co.,Ltd

Indications:

Treatment of essential hypertension.
This product is used for patients whose blood pressure cannot be adequately controlled by monotherapy.

Administration:

Amlodipine at a dose of 2.5 mg to 10 mg once daily is effective for the treatment of hypertension, and the effective dose of valsartan is 80 mg to 320 mg. In the clinical trials of valsartan and amlodipine tablets once daily, using 5 mg - 10 mg of amlodipine and 80 - 320 mg of valsartan, the antihypertensive effect increases with the increase of the dose.
The adverse reactions of valsartan are usually independent of the dose; the adverse reactions of amlodipine are both dose-dependent (mainly peripheral edema) and dose-independent, and the former is more common than the latter.
For patients whose blood pressure cannot be adequately controlled by monotherapy, this product can be used instead.
Add-on therapy: For patients whose blood pressure cannot be adequately controlled during monotherapy with amlodipine or valsartan, this product can be used for combination therapy.
For patients who experience dose-limiting adverse reactions during monotherapy with amlodipine or valsartan, this product can be used instead. Combine the components of the single drug at a lower dose to achieve blood pressure control. Most of the therapeutic effect can usually be achieved within 2 weeks after starting the medication or changing the dose.
Substitution therapy: For the convenience of administration, patients receiving combination therapy with amlodipine and valsartan can be switched to this product at the same dose for treatment.
Both amlodipine and valsartan can be taken with or without food. It is recommended to take this product with water.
Impairment of liver and kidney function
No dose adjustment is required for patients with mild to moderate renal impairment. Use with caution in patients with severe renal impairment. This product should also be used with caution in patients with liver impairment or biliary obstructive diseases.

Specifications:

80mg/5mg × 14 tablets